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Smoking Increases Risk of Vision Loss in Later Life
Monday, 01.11.2010, 12:47pm (GMT-4)
In 1982, the United States Surgeon General’s report stated that “there
is no single action an individual can take to reduce the risk of cancer
more effectively than quitting smoking, particularly cigarettes”—a
statement that is as true today as it was then.
When a person quits
smoking, the healing process begins within 20 minutes: the heart rate
drops toward normal, circulation improves, and the risk of having a
heart attack or stroke or of developing certain types of cancer
associated with smoking start to diminish.
Even seniors who quit after
many years can experience positive effects. A smoker who stops smoking
at age 65 cuts the risk of dying from a tobacco-related disease in
half.
And a recent study showed that elderly women who kick the habit
can reduce their chances of developing age-related macular degeneration
(AMD), a disease that can significantly reduce a person’s quality of
life.
AMD is a leading cause of vision loss in Americans 60
years of age and older. It doesn’t cause total blindness, but it causes
blurring or a blind spot in the part of the eye responsible for central
vision, the macula.
Clear central vision is necessary for reading,
driving, recognizing faces and doing detailed work. The greatest risk
factor for AMD is age, but family history (those with immediate family
members with the disease), race (whites are more likely than
African-Americans), gender (women at greater risk than men), obesity
and smoking may also increase the risk.
To determine how smoking
affects the risk of AMD later in life, University of California, Los
Angeles (UCLA) researchers analyzed data on a group of 1,958 women who
were participants of the Study of Osteoporotic Fractures, 75 of whom
were smokers.
The participants underwent retinal photographs at the
beginning of the study, when they were 78 years of age, and again five
years later at 83 years. The researchers looked for signs of AMD within
the photographs.
Overall, the women who smoked had an 11
percent higher rate of AMD than non-smoking women the same age. In
addition, 80-plus women who smoked were 5.5 times more likely than
their non-smoking counterparts to develop the condition.
Alcohol
consumption was also found to significantly elevate the risk of early
AMD. “The take-home message is that it’s never too late to quit
smoking,” said Dr. Anne Coleman, the study’s lead author and professor
of ophthalmology at the Jules Stein Eye Institute at UCLA.
“We found
that even older people’s eyes will benefit from kicking the habit.”
The researchers aren’t certain of the underlying biological reasons for
the link between smoking and increased risk of AMD for older women, but
they theorize that smoking may reduce the levels of antioxidants in the
blood, changing the blood flow to the eyes, thus reducing the amount of
pigmentation in the retina.
Dr. Paul Sieving, director of the
National Eye Institute, which along with the National Institute on
Aging funded the research, welcomed the findings.
“This study provides
yet another compelling reason to stop smoking and suggests that it is
never too late to quit.”
It is estimated that AMD already causes
visual impairment in approximately 1.7 million of the 34 million
Americans over age 65. And with 200,000 people developing the disease
each year in the U.S., that figure is expected to rise to nearly 3
million by 2020.
The National Eye Institute is conducting and
supporting numerous studies to learn more about AMD.
For example,
scientists are studying the possibility of transplanting healthy cells
into a diseased retina, investigating certain anti-inflammatory
treatments for the wet form of AMD, and evaluating families with a
history of the disease to understand genetic and hereditary factors
that may cause AMD.
The findings appear in the January edition of the American Journal of Ophthalmology.
By Madeline Ellis - HealthNews.com
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The H1N1 virus, commonly known as swine flu virus, could infect between 30 percent and 50 percent of the American population during the fall and winter and lead to as many as 1.8 million U.S. hospital admissions, the President's Council of Advisors on Science and Technology reported.
The report says 30,000 to 90,000 deaths are projected as part of a "plausible scenario" involving large outbreaks at schools, inadequate antiviral supplies and the virus peaking before vaccinations have time to be effective.
More on the story
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